Bharat Biotech's homegrown COVID-19 vaccine has shown an interim vaccine efficacy of 81% in late-stage clinical trials, the Indian company said on Wednesday.
The interim analysis was based on 43 recorded cases of COVID-19 in the trial of 25,800 participants, conducted in partnership with the Indian government's medical research body.
Thirty-six of the 43 cases were recorded in participants who received a placebo, compared with seven cases in people who were given the Bharat Biotech vaccine, pointing to an efficacy rate of 80.6%, the company said.
India had approved the vaccine, branded COVAXIN, in January without late-stage efficacy data, raising questions about its effectiveness.
India's vaccination drive, currently underway, includes COVAXIN and a vaccine developed by Oxford University and AstraZeneca.
Earlier this week, Indian Prime Minister Narendra Modi was inoculated with the first dose of COVAXIN.
Afghanistan airdropped commandos on Wednesday to pull survivors from the rubble of homes in mountainous eastern areas ravaged by earthquakes this week that have killed 1,400, as it ramped up efforts to deliver food, shelter and medical supplies.
President Volodymyr Zelenskyy will press for stronger pressure on Moscow as he meets allies in Denmark and France on Wednesday after Russian forces launched a sweeping air attack on Ukraine, damaging energy and transport infrastructure.
Chinese President Xi Jinping warned the world was facing a choice between peace or war as he held his country's largest-ever military parade on Wednesday, flanked by Russia's Vladimir Putin and North Korea's Kim Jong Un.
Widespread flooding has hit several parts of northern India, officials said, with more thunderstorms forecast for Wednesday as local media reported that 10,000 people were evacuated from the river banks in capital Delhi.
The US military killed 11 people on Tuesday in a strike on a vessel from Venezuela allegedly carrying illegal narcotics, President Donald Trump said, in the first known operation since his administration's recent deployment of warships to the southern Caribbean.