Tens of thousands of people across several cities in Europe and Asia took to the streets to express their solidarity with the Black Lives Matter movement in the US.
Large protests were held in London despite government advice to avoid gatherings due to the risk of coronavirus.
The largely peaceful protests saw people holding placards reading "Black Lives Matter" outside the parliament.
Meanwhile, in the German city of Hamburg, police used pepper spray to disperse large crowds gathered in honour of George Floyd.
Protestors in Paris were also seen ignoring government order to ban demonstrations and gathering at the Place de la Concorde, close to the Embassy.
Protests were also held in Warsaw, Berlin, Brisbane, Sydney, Tokyo, Seoul and Bangkok.
In the US, protestors gathered across several cities for the 12th straight day to demand an end to police brutality and racism.
Twenty-six people were killed and 17 were injured when gunmen opened fire at tourists in India's Jammu and Kashmir territory, police said on Wednesday, the worst such attack in the country in nearly two decades.
A strong earthquake with a magnitude of 6.2 shook Istanbul on Wednesday, Turkey's AFAD disaster agency said, one of the strongest quakes to strike the city of 16 million in recent years.
An Israeli airstrike on a school sheltering displaced families in northern Gaza killed at least 10 people, while another hit a children's hospital, local health authorities said, taking Wednesday's death toll to 20.
A Russian drone hit a bus carrying workers in the Ukrainian city of Marhanets early on Wednesday, killing nine people in a wave of attacks that targeted civilian infrastructure in east, south and central Ukraine, officials said.
Pope Francis' body was due to be moved to St Peter's Basilica on Wednesday to allow worshippers and the public to pay their final respects ahead of a funeral expected to bring US President Donald Trump and dozens of other world leaders to Rome.