England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
Italy face Northern Ireland in European playoffs, Sweden meet Ukraine
Italy will face Northern Ireland in the European playoffs in their bid to qualify for the 2026 FIFA World Cup while Sweden meet Ukraine as 16 teams learned the pathways that determine the four remaining European slots for the global tournament.
PSG defender Hakimi wins African Footballer of the Year
Paris St Germain's Achraf Hakimi was named African Footballer of the Year at the 2025 CAF Awards in Rabat on Wednesday, the first defender to claim the prize in 52 years as he finished ahead of Mohamed Salah and Victor Osimhen in the voting.
Holders Italy ease past Austria to reach Davis Cup semi-finals
Hosts Italy stayed on course for a Davis Cup 'three-peat' with a convincing victory over Austria in Bologna on Wednesday to set up a semi-final clash against Belgium.
New Zealand clinch ODI series against West Indies
Devon Conway and Rachin Ravindra's early attack helped New Zealand beat West Indies by five wickets with three balls to spare in a rain-curtailed second one-day international in Napier to seal the three-game series 2-0 on Wednesday.
Federer to be inducted into International Tennis Hall of Fame
Roger Federer will be inducted into the International Tennis Hall of Fame (ITHF) in an induction celebration set for August 2026 in Newport, Rhode Island, the ITHF said on Wednesday.
